Australia’s active hospital-based surveillance for severe childhood disease


Principal investigator 

Associate Professor Nick Wood

Despite immunisation coverage approaching 93%, pertussis continues to cause significant morbidity and mortality, particularly in very young Australian children. The aims of this surveillance are to determine the burden of disease from hospitalised pertussis, with special emphasis on the duration of hospitalisation, use of intensive care, death and disability. Possible sources of infection and comorbidities to severity of pertussis are examined. The NHMRC-funded Partnership Project (APP1113851) seeks to estimate the effectiveness of pertussis vaccination (either in infancy or maternal) against pertussis hospitalisations and emergency department presentations by comparing pertussis vaccination status in infants with pertussis <6 months of age and test-negative controls. These surveillance data will assist in optimising pertussis prevention strategies.